Mad Cow For other uses, see Mad Cow (disambiguation). Mad Cow is a villainess that made her first, and possibly only, appearance in The Doomies. Appearances The Doomies (intro) Trivia Mad Cow's name is a reference to mad-cow disease. This article is a stub. You can help T.U.F.F. Puppy Wiki by expanding it. Retrieved from "https://tuffpuppy.fandom.com/wiki/Mad_Cow_(female)?oldid=108153" Categories: Article stubs Females Characters Villains Non-D.O.O.M. One appearance Cow T.U.F.F. Puppy Minor Characters Community content is available under CC-BY-SA unless otherwise noted.